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Structure of 2318-25-4
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Ethyl 3-ethoxy-3-iminopropanoate hydrochloride features a stabilized iminium ion that enhances reactivity in polar aprotic solvents. This bench-stable derivative integrates readily into Mannich-type reactions and other C–C bond-forming processes, offering improved handling over free base analogs.
Ethyl 3-ethoxy-3-iminopropanoate hydrochloride serves as a versatile synthon in heterocyclic synthesis, enabling efficient access to pyrrolidine and piperidine scaffolds via reductive amination or cyclization protocols. Its iminium functionality exhibits high reactivity toward nucleophiles under mild conditions, while the ethoxy group provides stability and facilitates purification. The hydrochloride salt enhances solubility and handling, making it well-suited for bench-scale applications in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: