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CS-W001157 4
Total: USD 88.00

4-Bromo-2-(hydroxymethyl)phenol

  • CAS No. 2316-64-5

  • Cat. No. CS-W015481
  • Purity≥95%
  • MDL No.MFCD00004618

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-(hydroxymethyl)phenol|CS-W015481

Structure of 2316-64-5

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General Information

  • CAS No. 2316-64-5
  • Cat. No. CS-W015481
  • Purity ≥95%
  • MDL No. MFCD00004618
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇BrO₂
  • Molecular Weight 203.04
  • Synonym(s) Benzyl alcohol, 5-bromo-2-hydroxy-
  • SMILES C1=C(Br)C=CC(=C1CO)O

Description

5-Bromo-2-hydroxybenzyl alcohol was used in the synthesis of:7-bromo-2,3-diphenyl-5H-imidazo[2,1-b][1,3]benzoxazine6-bromo-2-octyl-4H-1,3,2-benzodioxaphosphorin 2-oxide4-bromo-2-(5-iodo-1H-indol-3-ylmethyl)- phenol

Application

4-Bromo-2-(hydroxymethyl)phenol serves as a versatile building block in medicinal chemistry and materials science, enabling efficient access to functionalized aromatic scaffolds. The molecule combines a bromine handle for palladium-catalyzed cross-coupling with a benzylic hydroxyl group amenable to derivatization or protection. Its bench-stable nature and compatibility with standard purification methods make it well-suited for multi-step synthesis workflows.

Synthesis

  • Route1

    References

    • Guo, Zong-Liang; Deng, Yan-Qiu; Zhong, Shi; Lu, Gui Tetrahedron Asymmetry, 2011 , vol. 22, # 13 p. 1395 - 1399
  • Route2

    References

    • Mochida Pharmaceutical Co., Ltd. Patent: US5587392 A1, 1996 ;
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 45, p. 2419 Justus Liebigs Annalen der Chemie, , vol. 302, p. 138

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.647
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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