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2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine

  • CAS No. 230615-69-7

  • Cat. No. CS-B1545
  • Purity≥98%
  • MDL No.MFCD11042283

*For research and further manufacturing use only, not for direct human use.

2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine|CS-B1545

Structure of 230615-69-7

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General Information

  • CAS No. 230615-69-7
  • Cat. No. CS-B1545
  • Purity ≥98%
  • MDL No. MFCD11042283
  • Storage 4°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₄F₃N₃O
  • Molecular Weight 285.27
  • Synonym(s) None
  • SMILES O=C(C(F)(F)F)N1CC(C2)C3=CC(N)=C(N)C=C3C2C1

Description

This trifluoromethyl ketone derivative integrates a fused tetrahydrobenzazepine core with diamino functionality, enabling direct incorporation into bioconjugation workflows. The electron-deficient carbonyl group facilitates nucleophilic addition under mild conditions, while the trifluoromethyl moiety enhances metabolic stability and lipophilicity for targeted probe development.

Application

1-(7,8-Diamino-1,2,4,5-tetrahydro-1,5-methano-3H-3-benzazepin-3-yl)-2,2,2-trifluoroethanone serves as a versatile building block for the synthesis of complex heterocyclic scaffolds and bioactive molecules. Its trifluoromethyl ketone functionality enables efficient imine formation and subsequent cyclization reactions, facilitating access to fused polycyclic systems. The molecule exhibits good bench stability and compatibility with common functional groups, supporting straightforward purification and integration into multi-step synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.35
  • LogP   1.8264
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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