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CS-W001157 4
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Oxazole-4-carboxylic acid

  • CAS No. 23012-13-7

  • Cat. No. CS-W019634
  • Purity≥98%
  • MDL No.MFCD06797151

*For research and further manufacturing use only, not for direct human use.

Oxazole-4-carboxylic acid|CS-W019634

Structure of 23012-13-7

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General Information

  • CAS No. 23012-13-7
  • Cat. No. CS-W019634
  • Purity ≥98%
  • MDL No. MFCD06797151
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₃NO₃
  • Molecular Weight 113.07
  • Synonym(s) 1,3-Oxazole-4-carboxylic acid
  • SMILES O=C(O)C=1N=COC1

Description

Oxazole-4-carboxylic acid features a heterocyclic oxazole ring fused to a carboxylic acid group, enabling direct integration into bioactive scaffolds. This configuration supports robust conjugation in medicinal chemistry and materials science applications, where stability and polar functionality are critical.

Application

Oxazole-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive heterocycles. Its carboxylic acid functionality facilitates amide coupling and esterification under standard conditions, while the oxazole ring provides metabolic stability and favorable pharmacokinetic properties. The compound exhibits bench stability, ease of purification, and compatibility with diverse functional groups, making it well-suited for modular synthesis of API candidates and targeted scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.33
  • LogP   0.3728
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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