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CS-W001157 4
Total: USD 88.00

tert-Butyl 3-(2-iodoethoxy)propanoate

  • CAS No. 2296723-16-3

  • Cat. No. CS-0103479
  • Purity≥95%
  • MDL No.MFCD32689526

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 3-(2-iodoethoxy)propanoate|CS-0103479

Structure of 2296723-16-3

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General Information

  • CAS No. 2296723-16-3
  • Cat. No. CS-0103479
  • Purity ≥95%
  • MDL No. MFCD32689526
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₇IO₃
  • Molecular Weight 300.13
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)CCOCCI

Description

tert-Butyl 3-(2-iodoethoxy)propanoate features a reactive iodoethyl ether handle for efficient coupling in synthetic transformations. This bench-stable, moisture-tolerant reagent integrates seamlessly into C–O bond-forming protocols and serves as a key intermediate in the construction of functionalized esters and bioconjugation scaffolds.

Application

tert-Butyl 3-(2-iodoethoxy)propanoate serves as a versatile bifunctional building block, enabling efficient Cu-catalyzed Ullmann-type etherification and Sonogashira coupling reactions. The iodide group facilitates reliable cross-coupling with terminal alkynes, while the ester moiety supports subsequent hydrolysis or reduction to access functionalized propanoic acid derivatives. Its tert-butyl ester offers excellent bench stability and simplified purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   2.1698
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   5

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