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CS-W001157 4
Total: USD 88.00

3-Aminobenzenethiol

  • CAS No. 22948-02-3

  • Cat. No. CS-W013510
  • Purity≥95%
  • MDL No.MFCD00007791

*For research and further manufacturing use only, not for direct human use.

3-Aminobenzenethiol|CS-W013510

Structure of 22948-02-3

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General Information

  • CAS No. 22948-02-3
  • Cat. No. CS-W013510
  • Purity ≥95%
  • MDL No. MFCD00007791
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇NS
  • Molecular Weight 125.19
  • Synonym(s) m-Amino Thiophenol
  • SMILES SC1=CC=CC(N)=C1

Description

3-Aminothiophenol was used as analyte during the fabrication of top-to-bottom joined system consisting of a silver nanowire and nanospheres. It was used in formation of polyaniline-analog monolayer on gold surface by anchoring to the gold substrate through the thiol moiety.

Application

3-Aminobenzenethiol serves as a versatile building block for sulfonamide and thiourea derivatives, enabling efficient access to bioactive heterocycles. Its ortho-aminothiol functionality offers excellent compatibility in copper-catalyzed click reactions and palladium-mediated coupling protocols. The compound exhibits good bench stability, facilitates straightforward purification via crystallization or column chromatography, and functions as a key intermediate in the synthesis of pharmaceutical scaffolds and functionalized materials.

Synthesis

  • Route1

    References

    • Qiao, Shu; Xie, Kun; Qi, Junsheng Chinese Journal of Chemistry, 2010 , vol. 28, # 8 p. 1441 - 1443
  • Route2

    References

    • Journal fuer Praktische Chemie (Leipzig), , vol. <2> 41, p. 197
  • Route3
    • 3,3'-Disulfanediyldianiline|CS-0356380
      40897-41-4
    • ~%
    • In-stock
      3-Aminobenzenethiol|CS-W013510
      22948-02-3

    References

    • Journal of the American Chemical Society, , vol. 96, # 19 p. 6081 - 6089

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3267
Class : 8
Packing Group : Ⅱ
Hazard Statements : H227-H302+H312+H332-H314-H318
Precautionary Statements : P210-P260-P261-P264-P270-P271-P280-P301+P330+P331-P302+P352-P304+P340-P330-P362+P364-P363-P370+P378-P403-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.5575
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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