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CS-W001157 4
Total: USD 88.00

3-Ethoxybenzaldehyde

  • CAS No. 22924-15-8

  • Cat. No. CS-W018146
  • Purity≥95%
  • MDL No.MFCD00016606

*For research and further manufacturing use only, not for direct human use.

3-Ethoxybenzaldehyde|CS-W018146

Structure of 22924-15-8

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General Information

  • CAS No. 22924-15-8
  • Cat. No. CS-W018146
  • Purity ≥95%
  • MDL No. MFCD00016606
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₂
  • Molecular Weight 150.18
  • Synonym(s) 3-Ethoxy Benzaldehyde
  • SMILES CCOC1=CC=CC(C=O)=C1

Description

3-Ethoxybenzaldehyde features a para-ethoxy substituent that enhances solubility and modulates electronic properties, enabling efficient incorporation into synthetic intermediates. This bench-stable aldehyde integrates readily in coupling reactions and serves as a key scaffold for pharmaceutical and agrochemical derivatization.

Application

3-Ethoxybenzaldehyde serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted aromatic scaffolds via standard coupling and condensation reactions. Its aldehyde functionality facilitates nucleophilic addition and imine formation, while the ortho-ethoxy group provides moderate electron donation and enhanced solubility. The compound exhibits good bench stability and is readily purified by distillation or chromatography, making it suitable for use in medicinal chemistry campaigns and process development workflows.

Synthesis

  • Route1
    • null|null
      75-03-6
    • 3-Hydroxybenzaldehyde Roxatidine Impurity|CS-0229483
      100-83-4
    • ~91%
    • In-stock
      3-Ethoxybenzaldehyde|CS-W018146
      22924-15-8

    References

    • Sarkar, Debayan; Venkateswaran, Ramanathapuram V. Tetrahedron Letters, 2011 , vol. 52, # 25 p. 3232 - 3233
  • Route2
    • 1-Ethoxy-3-Methylbenzene|CS-0740969
      621-32-9
    • ~%
    • In-stock
      3-Ethoxybenzaldehyde|CS-W018146
      22924-15-8
    • 1-Bromo-4-ethoxy-2-methylbenzene|CS-0151471
      68155-69-1

    References

    • Journal of Organic Chemistry, , vol. 46, # 22 p. 4562 - 4564
  • Route3
    • 3-Hydroxybenzaldehyde Roxatidine Impurity|CS-0229483
      100-83-4
    • ~%
    • In-stock
      3-Ethoxybenzaldehyde|CS-W018146
      22924-15-8

    References

    • Chemische Berichte, , vol. 28, p. 1999

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   1.8978
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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