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Structure of 2291360-60-4
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This piperidine-dione hydrochloride features a rigid isoindolinone core fused to a piperidine ring, delivering enhanced metabolic stability and improved solubility under physiological conditions. The electron-deficient isoindolinone moiety enables efficient coupling in late-stage functionalization, while the protonated piperidine enhances membrane permeability. Ideal for medicinal chemistry campaigns targeting CNS-penetrant scaffolds.
This compound serves as a versatile scaffold for medicinal chemistry campaigns, featuring a rigid isoindolinone core fused to a piperidine ring and bearing a reactive 2,6-dione functionality. The hydrochloride salt enhances solubility and stability, facilitating downstream functionalization via nucleophilic addition or reductive amination. Its well-defined stereochemistry and compatibility with common coupling reactions enable efficient access to complex heterocyclic architectures relevant to CNS-targeted drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319
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Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: