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CS-W001157 4
Total: USD 88.00

4,5-Dimethylthiazol-2-amine

  • CAS No. 2289-75-0

  • Cat. No. CS-W018469
  • Purity≥97%
  • MDL No.MFCD00462425

*For research and further manufacturing use only, not for direct human use.

4,5-Dimethylthiazol-2-amine|CS-W018469

Structure of 2289-75-0

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General Information

  • CAS No. 2289-75-0
  • Cat. No. CS-W018469
  • Purity ≥97%
  • MDL No. MFCD00462425
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈N₂S
  • Molecular Weight 128.20
  • Synonym(s) 4,5-Dimethyl-thiazol-2-ylamine
  • SMILES NC1=NC(C)=C(C)S1

Description

4,5-Dimethylthiazol-2-amine serves as a key heterocyclic scaffold in medicinal chemistry, featuring a sterically hindered thiazole ring with electron-donating methyl groups. This configuration enhances metabolic stability and facilitates incorporation into bioactive molecules. The amine functionality enables direct derivatization for probe development and conjugation workflows.

Application

4,5-Dimethylthiazol-2-amine serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling the construction of biologically relevant thiazole scaffolds. Its well-defined reactivity facilitates nucleophilic substitution and coupling reactions, particularly in the synthesis of heterocyclic compounds. The molecule exhibits good bench stability and functional group tolerance, supporting efficient purification and scalability in process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.34214
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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