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CS-W001157 4
Total: USD 88.00

2,3-Dihydrobenzofuran-5-boronic acid

  • CAS No. 227305-69-3

  • Cat. No. CS-W016099
  • Purity≥98%
  • MDL No.MFCD02681979

*For research and further manufacturing use only, not for direct human use.

2,3-Dihydrobenzofuran-5-boronic acid|CS-W016099

Structure of 227305-69-3

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General Information

  • CAS No. 227305-69-3
  • Cat. No. CS-W016099
  • Purity ≥98%
  • MDL No. MFCD02681979
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉BO₃
  • Molecular Weight None
  • Synonym(s) Boronic acid, B-(2,3-dihydro-5-benzofuranyl)-
  • SMILES C1=C2C(=CC=C1B(O)O)OCC2

Description

2,3-Dihydrobenzofuran-5-boronic acid delivers a stable, bench-ready boronate handle tethered to a rigid heterocyclic scaffold. This electron-rich moiety integrates efficiently in Suzuki-Miyaura cross-coupling reactions, enabling rapid access to functionalized biaryl architectures under standard conditions.

Application

2,3-Dihydrobenzofuran-5-boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. Its bench-stable nature and tolerance to diverse functional groups facilitate straightforward incorporation into complex molecular architectures. The compound functions as a key scaffold component in the synthesis of bioactive heterocycles and pharmaceutical intermediates, offering predictable reactivity and ease of purification in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   -0.6987
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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