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CS-W001157 4
Total: USD 88.00

2,6-Dichloro-7-methylpurine

  • CAS No. 2273-93-0

  • Cat. No. CS-W002180
  • Purity≥97%
  • MDL No.MFCD00039690

*For research and further manufacturing use only, not for direct human use.

2,6-Dichloro-7-methylpurine|CS-W002180

Structure of 2273-93-0

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General Information

  • CAS No. 2273-93-0
  • Cat. No. CS-W002180
  • Purity ≥97%
  • MDL No. MFCD00039690
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄Cl₂N₄
  • Molecular Weight 203.03
  • Synonym(s) 2,6-dichloro-7-methyl-purin
  • SMILES Clc1nc(Cl)c2c(n1)ncn2C

Description

2,6-Dichloro-7-methylpurine is a halogenated purine derivative featuring two chlorine atoms at the 2 and 6 positions and a methyl group at the 7 position. This electron-deficient scaffold enables direct incorporation into nucleoside analogs and serves as a key intermediate in medicinal chemistry for developing antiviral and anticancer agents.

Application

2,6-Dichloro-7-methylpurine serves as a key building block for purine-based scaffolds in medicinal chemistry and nucleoside analog synthesis. Its dichloro substitution pattern enables selective functionalization at C2 and C6, while the 7-methyl group enhances stability and modulates electronic properties. The compound exhibits good bench stability and facilitates efficient coupling reactions, making it well-suited for constructing biologically relevant heterocycles and advanced intermediates in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.6
  • LogP   1.6701
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   0

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