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Structure of 227199-07-7
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N-(Benzo[d][1,3]dioxol-5-yl)-2-chloroacetamide features a benzodioxole moiety linked to a chloroacetamide group, enabling efficient incorporation into bioconjugation workflows. This bench-stable reagent offers enhanced solubility in polar solvents and facilitates selective coupling under mild conditions.
N-(Benzo[d][1,3]dioxol-5-yl)-2-chloroacetamide serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles through nucleophilic substitution and cyclization reactions. Its benzo[d][1,3]dioxole moiety imparts metabolic stability and favorable lipophilicity, while the 2-chloroacetamide group provides a reactive handle for conjugation and scaffold elaboration. Bench-stable and readily purified by flash chromatography, it functions effectively in standard amide coupling and cycloaddition protocols.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: