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CS-W001157 4
Total: USD 88.00

2,6-Dibromo-4-(tert-butyl)pyridine

  • CAS No. 2256760-24-2

  • Cat. No. CS-1152483
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,6-Dibromo-4-(tert-butyl)pyridine|CS-1152483

Structure of 2256760-24-2

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General Information

  • CAS No. 2256760-24-2
  • Cat. No. CS-1152483
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁Br₂N
  • Molecular Weight 293.00
  • Synonym(s) None
  • SMILES BrC=1N=C(Br)C=C(C1)C(C)(C)C

Description

2,6-Dibromo-4-(tert-butyl)pyridine features a sterically shielded pyridine core with bromine substituents at the 2 and 6 positions, enabling selective metal-catalyzed coupling reactions. The tert-butyl group enhances solubility and stability under standard conditions, while the electron-deficient ring facilitates efficient palladium-mediated transformations in cross-coupling workflows.

Application

2,6-Dibromo-4-(tert-butyl)pyridine serves as a versatile building block for the synthesis of functionalized heterocycles and transition metal-catalyzed coupling substrates. The tert-butyl group enhances steric protection and bench stability, while the orthogonal bromine positions enable sequential cross-coupling reactions. Its defined regiochemistry facilitates predictable transformations in palladium-catalyzed processes, making it ideal for constructing complex pyridine-based scaffolds in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.9041
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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