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Structure of 2246802-17-3
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Tert-butyl 3-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene]azetidine-1-carboxylate features a sterically shielded boronate ester integrated into a strained azetidine framework. This configuration enables stable coupling in Suzuki-Miyaura reactions while maintaining reactivity under mild conditions. The tert-butyl carbamate group ensures excellent solubility and bench stability, facilitating straightforward handling in complex molecule assembly.
Tert-butyl 3-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene]azetidine-1-carboxylate serves as a stable, bench-ready boron building block for Suzuki-Miyaura coupling. The tetramethylboronate moiety enables efficient cross-coupling with aryl and vinyl halides under mild conditions. Its azetidine core provides a strained, bioactive heterocyclic scaffold relevant to medicinal chemistry. The tert-butyl ester facilitates straightforward deprotection, while the dioxaborolane group offers excellent functional group tolerance and ease of purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: