(R)-(Tetrahydrofuran-2-yl)methanol

Name: (R)-(Tetrahydrofuran-2-yl)methanol
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CAS No. 22415-59-4
Cat. No. CS-W013695
Purity≥98%
MDL No.MFCD03093085

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(R)-(Tetrahydrofuran-2-yl)methanol|CS-W013695

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General Information

CAS No. 22415-59-4
Cat. No. CS-W013695
Purity ≥98%
MDL No. MFCD03093085
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₀O₂
Molecular Weight 102.13
Synonym(s) (R)-Tetrahydrofurfuryl alcohol
SMILES OC[C@H]1CCCO1

Description

(R)-(Tetrahydrofuran-2-yl)methanol is a chiral building block featuring a hydroxymethyl group attached to the tetrahydrofuran ring. This configuration enables stereocontrolled synthesis in medicinal chemistry and natural product derivatization. The molecule exhibits enhanced solubility and stability under standard conditions, facilitating integration into multi-step transformations without racemization.

Application

(R)-(Tetrahydrofuran-2-yl)methanol serves as a chiral building block for the synthesis of bioactive molecules and pharmaceutical intermediates. Its hydroxymethyl functionality enables selective derivatization, while the tetrahydrofuran ring provides rigidity and stereochemical control. The compound exhibits good bench stability and compatibility with standard protecting group strategies, facilitating its use in multi-step syntheses involving nucleophilic substitutions and coupling reactions.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 29.46
LogP 0.1577
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Tetrahydrofuran compounds

Key Words

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(R)-(Tetrahydrofuran-2-yl)methanol

CAS No. 22415-59-4

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