Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

7-Bromoisoquinolin-1-ol

  • CAS No. 223671-15-6

  • Cat. No. CS-W002844
  • Molecule weight224.05
  • Purity≥98%
  • MDL No.MFCD01861851

*For research and further manufacturing use only, not for direct human use.

7-Bromoisoquinolin-1-ol|CS-W002844

Structure of 223671-15-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 223671-15-6
  • Cat. No. CS-W002844
  • Purity ≥98%
  • MDL No. MFCD01861851
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆BrNO
  • Molecular Weight 224.05
  • Synonym(s) 7-bromoisoquinolin-1(2H)-one
  • SMILES BrC1=CC2=C(C=CN=C2O)C=C1

Description

7-Bromoisoquinolin-1-ol features a bromine substituent at the 7-position of the isoquinoline core, enabling direct functionalization in cross-coupling reactions. The phenolic hydroxyl group provides a handle for derivatization and enhances solubility in polar solvents. This scaffold combines electron-deficient aromatic character with a reactive site, making it valuable for synthesizing bioactive molecules and advanced ligands in catalysis.

Application

7-Bromoisoquinolin-1-ol serves as a versatile building block for the synthesis of isoquinoline-based scaffolds, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromine handle. The phenolic hydroxyl group provides a site for derivatization or protection, enhancing functional group tolerance in multi-step syntheses. Its bench-stable solid form facilitates handling and purification, making it suitable for medicinal chemistry campaigns and process development.

Synthesis

  • Route1
    • 3-(4-Bromophenyl)acrylic acid Ozagrel Impurity|CS-0228823
      1200-07-3
    • ~%
    • In-stock
      7-Bromoisoquinolin-1-ol|CS-W002844
      223671-15-6

    References

    • Synthetic Communications, , vol. 35, # 5 p. 725 - 730
  • Route2
    • null|null
      27465-66-3
    • ~%
    • In-stock
      7-Bromoisoquinolin-1-ol|CS-W002844
      223671-15-6

    References

    • Synthetic Communications, , vol. 35, # 5 p. 725 - 730
  • Route3

    References

    • US6339099 B1, ; Page column 45-46 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   33.12
  • LogP   2.7029
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 7-Bromoisoquinolin-1-ol sigma7-Bromoisoquinolin-1-ol manufacturer7-Bromoisoquinolin-1-ol price7-Bromoisoquinolin-1-ol structure7-Bromoisoquinolin-1-ol SDSbuy 7-Bromoisoquinolin-1-ol7-Bromoisoquinolin-1-ol supplier7-Bromoisoquinolin-1-ol uses7-Bromoisoquinolin-1-ol molecular weightprice of 7-Bromoisoquinolin-1-ol7-Bromoisoquinolin-1-ol chemical name formula of 7-Bromoisoquinolin-1-ol
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label