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CS-W001157 4
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1-Vinylazepan-2-one

  • CAS No. 2235-00-9

  • Cat. No. CS-0077097
  • Purity≥97%
  • MDL No.MFCD00080693

*For research and further manufacturing use only, not for direct human use.

1-Vinylazepan-2-one|CS-0077097

Structure of 2235-00-9

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General Information

  • CAS No. 2235-00-9
  • Cat. No. CS-0077097
  • Purity ≥97%
  • MDL No. MFCD00080693
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₃NO
  • Molecular Weight 139.19
  • Synonym(s) N-Vinyl-epsilon-caprolactam
  • SMILES O=C1N(C=C)CCCCC1

Description

m-PEG2-acid is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Synthesis

  • Route1

    References

    • US2806847 , ; US2806848 , ;
  • Route2
    • 1,4-Diethoxybutane|CS-0444651
      13344-00-8
    • ~81%
    • 1-Vinylazepan-2-one|CS-0077097
      2235-00-9

    References

    • Boettcher, Arnd; Pinkos, Rolf; Preiss, Thomas; Lorenz, Rudolf Erich Patent: US2003/28035 A1, 2003 ;
  • Route3

    References

    • Gazzetta Chimica Italiana, , vol. 123, # 8 p. 457 - 462

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312-H317-H319-H372
Precautionary Statements : P260-P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   20.31
  • LogP   1.5325
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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