Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Bicyclo[1.1.1]pentane-1-carboxylic acid

  • CAS No. 22287-28-1

  • Cat. No. CS-0036907
  • Purity≥95%
  • MDL No.MFCD19228106

*For research and further manufacturing use only, not for direct human use.

Bicyclo[1.1.1]pentane-1-carboxylic acid|CS-0036907

Structure of 22287-28-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 22287-28-1
  • Cat. No. CS-0036907
  • Purity ≥95%
  • MDL No. MFCD19228106
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈O₂
  • Molecular Weight None
  • Synonym(s) bicyclo[1.1.1]pentane-3-carboxylic acid
  • SMILES C1C2CC1(C2)C(=O)O

Description

Bicyclo[1.1.1]pentane-1-carboxylic acid features a rigid, strain-engineered cage structure that imparts exceptional metabolic stability and enhanced lipophilicity. This unique scaffold integrates readily into bioactive molecules, delivering improved membrane permeability and pharmacokinetic profiles in drug discovery applications.

Application

Bicyclo[1.1.1]pentane-1-carboxylic acid serves as a robust bioisostere for tert-butyl and phenyl groups in medicinal chemistry, offering enhanced metabolic stability and improved physicochemical properties. Its rigid, three-dimensional structure enables favorable binding interactions while maintaining excellent bench stability and compatibility with standard coupling reactions. The carboxylic acid functionality facilitates direct derivatization or salt formation, supporting efficient purification and downstream functionalization in API development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.3
  • LogP   0.8711
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Bicyclo[1.1.1]pentane-1-carboxylic acid sigmaBicyclo[1.1.1]pentane-1-carboxylic acid manufacturerBicyclo[1.1.1]pentane-1-carboxylic acid priceBicyclo[1.1.1]pentane-1-carboxylic acid structureBicyclo[1.1.1]pentane-1-carboxylic acid SDSbuy Bicyclo[1.1.1]pentane-1-carboxylic acidBicyclo[1.1.1]pentane-1-carboxylic acid supplierBicyclo[1.1.1]pentane-1-carboxylic acid usesBicyclo[1.1.1]pentane-1-carboxylic acid molecular weightprice of Bicyclo[1.1.1]pentane-1-carboxylic acidBicyclo[1.1.1]pentane-1-carboxylic acid chemical name formula of Bicyclo[1.1.1]pentane-1-carboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label