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Structure of 22282-72-0
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2-Hydroxy-isonicotinic acid features a strategically positioned hydroxyl group adjacent to a pyridine nitrogen, enabling strong chelation with metal ions and enhancing solubility in polar solvents. This structural motif facilitates integration into coordination complexes and bioactive scaffolds, offering utility in catalysis, pharmaceutical development, and materials chemistry under standard bench conditions.
2-Hydroxy-isonicotinic acid serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling direct access to bioactive heterocyclic scaffolds. Its ortho-hydroxypyridine motif facilitates metal chelation and enhances solubility, while the carboxylic acid group supports straightforward derivatization via amide coupling, esterification, or activation for nucleophilic substitution. The compound exhibits excellent bench stability and is compatible with standard purification methods, making it a reliable reagent for the synthesis of pharmaceutical intermediates and ligand frameworks.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: