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7-Amino-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one

  • CAS No. 22245-92-7

  • Cat. No. CS-0004303
  • Molecule weight176.22
  • Purity≥97%
  • MDL No.MFCD09260841

*For research and further manufacturing use only, not for direct human use.

7-Amino-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one|CS-0004303

Structure of 22245-92-7

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General Information

  • CAS No. 22245-92-7
  • Cat. No. CS-0004303
  • Purity ≥97%
  • MDL No. MFCD09260841
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂N₂O
  • Molecular Weight 176.22
  • Synonym(s) 7-Aminodihydrohomocarbostyril
  • SMILES O=C(CCC1)NC(C1=C2)=CC=C2N

Synthesis

  • Route1

    References

    • Osadchii, S. A.; Kochubei, N. V. Russian Journal of Applied Chemistry, 1994 , vol. 67, # 11.2 p. 1674 - 1676 Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1994 , vol. 67, # 11 p. 1909 - 1911
  • Route2
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      939043-29-5
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      22246-68-0
    • 7-Amino-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one|CS-0004303
      22245-92-7

    References

    • Camus, Laure; Chudasama, Reshma; Day, Caroline Jane; Deshmukh, Deepali; Gleason, John Gerald; Harling, John David; Lee, Chao-Pin; Saklatvala, Paula; Senger, Stefan; Vallance, Sarah; Watson, John; Watson, Nigel Stephen; Young, Robert John; Yuan, Barbara Patent: US2008/306045 A1, 2008 ; Location in patent: Page/Page column 13 ;
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    References

    • Weinberg, Linda R.; Albom, Mark S.; Angeles, Thelma S.; Husten, Jean; Lisko, Joseph G.; McHugh, Robert J.; Milkiewicz, Karen L.; Murthy, Seetha; Ott, Gregory R.; Theroff, Jay P.; Tripathy, Rabindranath; Underiner, Ted L.; Zificsak, Craig A.; Dorsey, Bruce D. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 164 - 167

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   1.5436
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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