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Structure of 22227-25-4
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3-(Trifluoromethyl)benzohydrazide features a trifluoromethyl group that imparts enhanced electron-withdrawing character and metabolic stability. This compound integrates readily into hydrazone-based conjugation strategies, offering improved solubility and reactivity under standard bench conditions.
3-(Trifluoromethyl)benzohydrazide serves as a versatile building block in medicinal chemistry, enabling the construction of hydrazine-containing heterocycles and bioactive scaffolds. Its trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the hydrazide functionality facilitates condensation reactions with aldehydes and ketones to form hydrazones—key intermediates in drug discovery workflows. The compound exhibits good bench stability and is readily purified by recrystallization, supporting its use in scalable synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: