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CS-W001157 4
Total: USD 88.00

4-Fluorobenzothioamide

  • CAS No. 22179-72-2

  • Cat. No. CS-0187014
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Fluorobenzothioamide|CS-0187014

Structure of 22179-72-2

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Description

4-Fluorobenzothioamide features a fluorinated aromatic ring paired with a thioamide functional group, delivering enhanced electronic effects and metabolic stability. This combination enables direct incorporation into heterocyclic scaffolds and facilitates conjugation in medicinal chemistry workflows. The compound exhibits good solubility in common organic solvents and maintains stability under standard bench conditions.

Application

4-Fluorobenzothioamide serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds through cyclization reactions. Its fluorinated aryl moiety enhances metabolic stability and modulates electronic properties, while the thioamide group provides reliable reactivity in amide bond formation and transition metal-catalyzed coupling processes. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step syntheses requiring functional group tolerance and predictable reactivity.

General Information

  • CAS No. 22179-72-2
  • Cat. No. CS-0187014
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆FNS
  • Molecular Weight 155.19
  • Synonym(s) 4-Fluorothiobenzamide
  • SMILES C1=C(C=CC(=C1)F)C(=S)N

Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.4599
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group :
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

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