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CS-W001157 4
Total: USD 88.00

1-ETHYL 4-METHYL BENZENE-1,4-DICARBOXYLATE

  • CAS No. 22163-52-6

  • Cat. No. CS-0059909
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-ETHYL 4-METHYL BENZENE-1,4-DICARBOXYLATE|CS-0059909

Structure of 22163-52-6

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General Information

  • CAS No. 22163-52-6
  • Cat. No. CS-0059909
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₂O₄
  • Molecular Weight 208.21
  • Synonym(s) 1,4-Benzenedicarboxylic acid 1-ethyl 4-methyl ester
  • SMILES C=1(C=CC(=CC1)C(=O)OC)C(=O)OCC

Description

Ethyl methyl terephthalate serves as a key diester intermediate in polyester synthesis, featuring a rigid aromatic core flanked by ethyl and methyl ester groups. This combination delivers enhanced solubility in organic solvents and improved thermal stability during polymerization processes.

Application

Ethyl methyl terephthalate serves as a versatile diester building block in synthetic organic chemistry, enabling efficient access to aromatic polyesters and functionalized terephthalate scaffolds. Its bench-stable nature, combined with orthogonal reactivity of ester and methyl groups, facilitates selective transformations in multi-step synthesis. This compound functions effectively in standard coupling protocols and is well-suited for scale-up applications requiring predictable reactivity and straightforward purification.

Synthesis

  • Route1
    • null|null
      67-56-1
    • null|null
      15226-74-1
    • In-stock
      Ethyl 4-bromobenzoate|CS-W007730
      5798-75-4
    • ~92%
    • In-stock
      1-ETHYL 4-METHYL BENZENE-1,4-DICARBOXYLATE|CS-0059909
      22163-52-6

    References

    • Baburajan; Senthilkumaran; Elango, Kuppanagounder P. New Journal of Chemistry, 2013 , vol. 37, # 10 p. 3050 - 3056
  • Route2
    • null|null
      64-17-5
    • In-stock
      Methyl 4-carbamoylbenzoate|CS-0454794
      6757-31-9
    • ~73%
    • In-stock
      1-ETHYL 4-METHYL BENZENE-1,4-DICARBOXYLATE|CS-0059909
      22163-52-6

    References

    • Fisher; Caroon; Stabler; Lundberg; Zaidi; Sorensen; Sparacino; Muchowski Canadian Journal of Chemistry, 1994 , vol. 72, # 1 p. 142 - 145
  • Route3

    References

    • Fisher; Caroon; Stabler; Lundberg; Zaidi; Sorensen; Sparacino; Muchowski Canadian Journal of Chemistry, 1994 , vol. 72, # 1 p. 142 - 145

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   52.6
  • LogP   1.6499
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   3

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