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Structure of 221340-53-0
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This trifluoromethyl ketone derivative integrates a piperidinyl amine handle for conjugation, enabling rapid derivatization in synthetic workflows. The hydrochloride salt enhances solubility and stability under standard conditions, supporting efficient incorporation into bioconjugates and pharmaceutical intermediates.
1-(4-Aminopiperidin-1-yl)-2,2,2-trifluoroethan-1-one hydrochloride serves as a versatile building block for medicinal chemistry, enabling the efficient construction of trifluoromethylated piperidine scaffolds. The electrophilic trifluoromethyl ketone moiety reacts readily with amines and hydrazines under mild conditions, facilitating rapid diversification. Its bench-stable solid form and excellent functional group tolerance support scalable synthesis and straightforward purification, making it ideal for high-throughput library generation and target-oriented compound development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: