2-[(tert-Butoxy)carbonyl]-2-azabicyclo[2.1.1]hexane-4-carboxylic acid

Name: 2-[(tert-Butoxy)carbonyl]-2-azabicyclo[2.1.1]hexane-4-carboxylic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 220598-45-8
Cat. No. CS-0030237
Purity≥98%
MDL No.MFCD28501912

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-[(tert-Butoxy)carbonyl]-2-azabicyclo[2.1.1]hexane-4-carboxylic acid|CS-0030237

Structure of 220598-45-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 220598-45-8
Cat. No. CS-0030237
Purity ≥98%
MDL No. MFCD28501912
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₇NO₄
Molecular Weight 227.26
Synonym(s) 2-(tert-Butoxycarbonyl)-2-azabicyclo[2.1.1]hexane-4-carboxylic acid
SMILES O=C(C12CN(C(OC(C)(C)C)=O)C(C2)C1)O

Description

This azabicyclic carboxylic acid features a tert-butoxycarbonyl-protected amine within a strained bicyclic framework, enabling direct incorporation into peptide backbones. The rigid scaffold imparts conformational control, while the Boc group ensures stability and ease of deprotection under mild acidic conditions.

Application

2-[(tert-Butoxy)carbonyl]-2-azabicyclo[2.1.1]hexane-4-carboxylic acid serves as a robust, bench-stable building block for the synthesis of constrained azabicyclic scaffolds. Its tert-butyl ester functionality enables straightforward deprotection under mild acidic conditions, while the bicyclic core imparts conformational rigidity ideal for medicinal chemistry exploration. The carboxylic acid group facilitates efficient coupling reactions, supporting diverse functionalization in peptide and small-molecule synthesis.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 66.84
LogP 1.4705
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Bridge Rings compounds Other bridge ring compounds

Building Blocks Skeleton Fatty ring compounds Cyclobutane compounds

Key Words

220598-45-8 sigma220598-45-8 manufacturer220598-45-8 price220598-45-8 structure220598-45-8 SDSbuy 220598-45-8220598-45-8 supplier220598-45-8 uses220598-45-8 molecular weightprice of 220598-45-8220598-45-8 chemical name formula of 220598-45-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-[(tert-Butoxy)carbonyl]-2-azabicyclo[2.1.1]hexane-4-carboxylic acid

CAS No. 220598-45-8

Recommended Products