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Structure of 220514-28-3
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Methyl 5-bromo-2-methyl-3-nitrobenzoate features a trifunctional aromatic core with strategically positioned bromo, methyl, and nitro groups. This electron-deficient scaffold enables direct coupling in cross-coupling reactions and serves as a key intermediate in the synthesis of bioactive heterocycles and functionalized pharmaceuticals.
Methyl 5-bromo-2-methyl-3-nitrobenzoate serves as a versatile synthetic intermediate for functionalized aromatic systems. The molecule combines a bromo group for cross-coupling reactions, a nitro group amenable to reduction and subsequent substitution, and a methyl substituent that influences electronic effects and regioselectivity. Its bench-stable nature and compatibility with palladium-catalyzed transformations enable efficient access to substituted biaryls and heterocyclic scaffolds in medicinal chemistry and materials synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: