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CS-W001157 4
Total: USD 88.00

Fmoc-Cpg-OH

  • CAS No. 220497-61-0

  • Cat. No. CS-W022724
  • Purity≥98%
  • MDL No.MFCD01311751

*For research and further manufacturing use only, not for direct human use.

Fmoc-Cpg-OH|CS-W022724

Structure of 220497-61-0

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General Information

  • CAS No. 220497-61-0
  • Cat. No. CS-W022724
  • Purity ≥98%
  • MDL No. MFCD01311751
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₂₃NO₄
  • Molecular Weight 365.42
  • Synonym(s) None
  • SMILES O=C(O)[C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C4CCCC4

Description

Fmoc-Cpg-OH serves as a solid-phase support for oligonucleotide synthesis, combining a CPG (controlled pore glass) matrix with a labile Fmoc-protected amino linker. This configuration enables efficient, stepwise chain elongation while maintaining high coupling efficiency and ease of cleavage under standard conditions.

Application

Fmoc-Cpg-OH serves as a robust solid-phase support for oligonucleotide synthesis, enabling efficient chain elongation via standard phosphoramidite coupling protocols. The Fmoc-protected aminooxy group facilitates site-specific conjugation and post-synthetic modifications, while the CPG (controlled pore glass) matrix ensures high loading capacity, excellent solubility, and compatibility with automated synthesis platforms. Its bench-stable, moisture-resistant properties simplify handling and storage, making it ideal for routine and scale-up applications in nucleic acid research and therapeutic development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   4.1685
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   5

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