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CS-W001157 4
Total: USD 88.00

4-(2-Hydroxyethoxy)benzaldehyde

  • CAS No. 22042-73-5

  • Cat. No. CS-M2027
  • Molecule weight166.17
  • Purity≥98%
  • MDL No.MFCD00191450

*For research and further manufacturing use only, not for direct human use.

4-(2-Hydroxyethoxy)benzaldehyde|CS-M2027

Structure of 22042-73-5

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General Information

  • CAS No. 22042-73-5
  • Cat. No. CS-M2027
  • Purity ≥98%
  • MDL No. MFCD00191450
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₃
  • Molecular Weight 166.17
  • Synonym(s) Benzaldehyde, p-(2-hydroxyethoxy)-; N-(2-hydroxyethoxy)benzaldehyde
  • SMILES O=CC1=CC=C(OCCO)C=C1

Description

4-(2-Hydroxyethoxy)benzaldehyde features a hydrophilic ethylene glycol linker attached to a phenolic ring, enhancing solubility in aqueous systems. The aldehyde group enables direct conjugation or derivatization in synthetic workflows. This bifunctional architecture supports applications in bioconjugation, polymer functionalization, and the design of responsive materials.

Application

4-(2-Hydroxyethoxy)benzaldehyde serves as a versatile building block in medicinal chemistry and materials science, enabling efficient derivatization via aldehyde and hydroxyl functionalities. Its bench-stable nature and compatibility with standard coupling reactions facilitate straightforward synthesis of bioactive molecules and functional polymers.

Synthesis

  • Route1
    • p-Hydroxybenzaldehyde Bisoprolol Impurity|CS-0229513
      123-08-0
    • null|null
      107-07-3
    • ~85%
    • In-stock
      4-(2-Hydroxyethoxy)benzaldehyde|CS-M2027
      22042-73-5

    References

    • Watanabe, Hiroyuki; Ono, Masahiro; Kimura, Hiroyuki; Kagawa, Shinya; Nishii, Ryuichi; Fuchigami, Takeshi; Haratake, Mamoru; Nakayama, Morio; Saji, Hideo Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 21 p. 6519 - 6522
  • Route2
    • p-Hydroxybenzaldehyde Bisoprolol Impurity|CS-0229513
      123-08-0
    • null|null
      540-51-2
    • ~80%
    • In-stock
      4-(2-Hydroxyethoxy)benzaldehyde|CS-M2027
      22042-73-5

    References

    • L. MOLTENI and C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A Patent: WO2004/35590 A2, 2004 ; Location in patent: Page 22-23 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   0.8702
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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