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Structure of 220353-22-0
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4-Amino-2,6-difluorophenol hydrochloride features a highly reactive amino group flanked by two electron-withdrawing fluorine atoms, enhancing its utility in coupling reactions. The hydrochloride salt form ensures improved solubility and stability under standard conditions, facilitating use in pharmaceutical intermediates and functional material synthesis.
4-Amino-2,6-difluorophenol hydrochloride serves as a key building block in the synthesis of fluorinated aromatic scaffolds, enabling efficient access to medicinally relevant heterocycles. Its ortho-difluoro substitution pattern facilitates directed metalation and nucleophilic aromatic substitution, while the amine and phenolic functionalities offer orthogonal reactivity for downstream derivatization. The hydrochloride salt enhances bench stability and solubility, simplifying handling and purification in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: