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CS-W001157 4
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1,2,3,4-Tetrahydroisoquinoline-7-carboxylic acid hydrochloride

  • CAS No. 220247-71-2

  • Cat. No. CS-0042128
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1,2,3,4-Tetrahydroisoquinoline-7-carboxylic acid hydrochloride|CS-0042128

Structure of 220247-71-2

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General Information

  • CAS No. 220247-71-2
  • Cat. No. CS-0042128
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂ClNO₂
  • Molecular Weight 213.66
  • Synonym(s) None
  • SMILES Cl.OC(=O)C1=CC2=C(CCNC2)C=C1

Description

This tetrahydroisoquinoline derivative features a carboxylic acid group at the 7-position, enabling direct conjugation or derivatization. The hydrochloride salt form enhances solubility and stability in aqueous systems, facilitating use in synthetic transformations and medicinal chemistry applications.

Application

1,2,3,4-Tetrahydroisoquinoline-7-carboxylic acid hydrochloride serves as a versatile scaffold for medicinal chemistry and natural product synthesis. Its carboxylic acid functionality enables direct coupling reactions and derivatization under standard conditions. The hydrochloride salt enhances solubility and bench stability, facilitating purification and handling in multi-step syntheses. Functions as a key building block for heterocyclic systems and bioactive molecules requiring the tetrahydroisoquinoline core.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   1.4523
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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