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CS-W001157 4
Total: USD 88.00

(3R,7aS)-7a-methyl-3-(trichloromethyl)tetrahydro-1H,3H-pyrrolo[1,2-c]oxazol-1-one

  • CAS No. 220200-88-4

  • Cat. No. CS-0502780
  • Molecule weight258.53
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3R,7aS)-7a-methyl-3-(trichloromethyl)tetrahydro-1H,3H-pyrrolo[1,2-c]oxazol-1-one|CS-0502780

Structure of 220200-88-4

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General Information

  • CAS No. 220200-88-4
  • Cat. No. CS-0502780
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀Cl₃NO₂
  • Molecular Weight 258.53
  • Synonym(s) (3R,7aS)-3-(Trichloromethyl)tetrahydropyrrolo[1,2-c]oxazol-1(3H)-one
  • SMILES ClC(Cl)(Cl)[C@@H]1N2[C@](CCC2)(C)C(=O)O1

Synthesis

  • Route1
    • 3-(Trichloromethyl)tetrahydro-1H,3H-pyrrolo[1,2-c]oxazol-1-one|CS-0092698
      118916-60-2
    • null|null
      74-88-4
    • ~76%
    • (3R,7aS)-7a-methyl-3-(trichloromethyl)tetrahydro-1H,3H-pyrrolo[1,2-c]oxazol-1-one|CS-0502780
      220200-88-4

    References

    • Su, Bo; Deng, Meng; Wang, Qingmin European Journal of Organic Chemistry, 2013 , # 10 p. 1979 - 1985
  • Route2
    • null|null
      74-88-4
    • ~62%
    • (3R,7aS)-7a-methyl-3-(trichloromethyl)tetrahydro-1H,3H-pyrrolo[1,2-c]oxazol-1-one|CS-0502780
      220200-88-4

    References

    • NEUREN PHARMACEUTICALS LIMITED; NEUREN PHARMACEUTICALS INC. Patent: WO2006/127702 A2, 2006 ; Location in patent: Page/Page column 30 ;
  • Route3
    • L-Proline Enalapril  Impurity|CS-0229432
      147-85-3
    • ~%
    • (3R,7aS)-7a-methyl-3-(trichloromethyl)tetrahydro-1H,3H-pyrrolo[1,2-c]oxazol-1-one|CS-0502780
      220200-88-4

    References

    • Su, Bo; Deng, Meng; Wang, Qingmin European Journal of Organic Chemistry, 2013 , # 10 p. 1979 - 1985

Safety Information

Download SDS
GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   29.54
  • LogP   2.094
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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