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CS-W001157 4
Total: USD 88.00

1,4-Benzodioxan-6-amine

  • CAS No. 22013-33-8

  • Cat. No. CS-W001112
  • Purity≥98%
  • MDL No.MFCD00006824

*For research and further manufacturing use only, not for direct human use.

1,4-Benzodioxan-6-amine|CS-W001112

Structure of 22013-33-8

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General Information

  • CAS No. 22013-33-8
  • Cat. No. CS-W001112
  • Purity ≥98%
  • MDL No. MFCD00006824
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₂
  • Molecular Weight 151.16
  • Synonym(s) 6-Amino-1,4-benzodioxane; 1,4-Benzodioxan-6-amine
  • SMILES Nc1ccc2c(c1)OCCO2

Description

1,4-Benzodioxan-6-amine was used in the synthesis of N-(2-hydroxy-ethyl)-2,3-didehydroazapodophyllotoxins having anti-tumor activity and dioxanoacridinones.

Synthesis

  • Route1

    References

    • Dey, Raju; Mukherjee, Nirmalya; Ahammed, Sabir; Ranu, Brindaban C. Chemical Communications, 2012 , vol. 48, # 64 p. 7982 - 7984
  • Route2

    References

    • Zorina, L. N.; Safiev, O. G.; Rakhmankulov, D. L.; Paushkin, Ya. M. Doklady Chemistry, 1987 , vol. 296, # 10 p. 444 - 446 Dokl. Akad. Nauk SSSR Ser. Khim., 1987 , vol. 296, # 4 p. 887 - 890
  • Route3
    • 7-Nitro-2,3-dihydro-1,4-benzodioxin-6-amine|CS-0220143
      62140-78-7
    • ~89%
    • In-stock
      1,4-Benzodioxan-6-amine|CS-W001112
      22013-33-8

    References

    • Mateu; Capilla; Harrak; Pujol Tetrahedron, 2002 , vol. 58, # 26 p. 5241 - 5250

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   44.48
  • LogP   1.04
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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