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CS-W001157 4
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(S)-3,3'-Diiodo-2,2'-bis(methoxymethoxy)-1,1'-binaphthalene

  • CAS No. 219583-87-6

  • Cat. No. CS-0086457
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-3,3'-Diiodo-2,2'-bis(methoxymethoxy)-1,1'-binaphthalene|CS-0086457

Structure of 219583-87-6

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General Information

  • CAS No. 219583-87-6
  • Cat. No. CS-0086457
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₄H₂₀I₂O₄
  • Molecular Weight 626.22
  • Synonym(s) WPT18N/A1-7N/A3B
  • SMILES IC1=CC2=CC=CC=C2[C@@]([C@@]3=C(C=CC=C4)C4=CC(I)=C3OCOC)=C1OCOC

Description

This chiral binaphthyl derivative features iodine substituents at the 3,3′-positions and methoxymethoxy groups flanking the 2,2′-positions, enabling robust coupling reactions in asymmetric synthesis. The sterically defined scaffold delivers high enantioselectivity in transition metal-catalyzed transformations, while its bench-stable nature supports reliable handling under standard conditions.

Application

(S)-3,3'-Diiodo-2,2'-bis(methoxymethoxy)-1,1'-binaphthalene serves as a stereochemically defined chiral building block for asymmetric synthesis. The diiodo functionality enables palladium-catalyzed cross-coupling reactions, while the methoxymethoxy groups provide orthogonal protection and enhance solubility. This compound facilitates the construction of complex binaphthyl-based scaffolds with high enantiomeric purity, offering reliable bench stability and straightforward purification—ideal for applications in catalytic asymmetric synthesis and ligand development.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H318-H413
Precautionary Statements : P273-P280-P501

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Computational Chemistry Data

  • TPSA   36.92
  • LogP   6.8346
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   7

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