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Structure of 21900-62-9
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4-Isopropylbenzoyl chloride features a sterically hindered aromatic acyl group that enhances selectivity in amide bond formation. This bench-stable reagent couples efficiently with amines under standard conditions, delivering high yields with minimal side reactions. The isopropyl substituent imparts enhanced solubility in organic media and reduces hydrolytic instability compared to unsubstituted analogs.
4-Isopropylbenzoyl chloride serves as a versatile acylating agent in synthetic organic chemistry, enabling efficient amide and ester formation under mild conditions. Its aromatic acyl group provides enhanced stability and solubility compared to simpler acid chlorides, while the isopropyl substituent offers favorable steric and electronic properties for downstream functionalization. The reagent exhibits excellent reactivity in standard coupling protocols and is well-suited for use in peptide synthesis, pharmaceutical intermediate preparation, and heterocycle construction where controlled acylation is required.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1760
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302-H314-H332
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Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P312-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P312-P330-P363-P405-P501
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Lot numbers can be found on the outside label of a product: