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CS-W001157 4
Total: USD 88.00

4-Isopropylbenzoyl chloride

  • CAS No. 21900-62-9

  • Cat. No. CS-0313249
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Isopropylbenzoyl chloride|CS-0313249

Structure of 21900-62-9

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Description

4-Isopropylbenzoyl chloride features a sterically hindered aromatic acyl group that enhances selectivity in amide bond formation. This bench-stable reagent couples efficiently with amines under standard conditions, delivering high yields with minimal side reactions. The isopropyl substituent imparts enhanced solubility in organic media and reduces hydrolytic instability compared to unsubstituted analogs.

Application

4-Isopropylbenzoyl chloride serves as a versatile acylating agent in synthetic organic chemistry, enabling efficient amide and ester formation under mild conditions. Its aromatic acyl group provides enhanced stability and solubility compared to simpler acid chlorides, while the isopropyl substituent offers favorable steric and electronic properties for downstream functionalization. The reagent exhibits excellent reactivity in standard coupling protocols and is well-suited for use in peptide synthesis, pharmaceutical intermediate preparation, and heterocycle construction where controlled acylation is required.

General Information

  • CAS No. 21900-62-9
  • Cat. No. CS-0313249
  • Purity ≥98%
  • MDL No. None
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁ClO
  • Molecular Weight 182.65
  • Synonym(s) None
  • SMILES CC(C)C1=CC=C(C=C1)C(=O)Cl

Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   N/A
  • H_Donors   N/A
  • Rotatable_Bonds   N/A

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group :
Hazard Statements : H302-H314-H332
Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P312-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P312-P330-P363-P405-P501

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