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Structure of 21883-13-6
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4-Methoxy-2-methylbenzonitrile features a strategically positioned nitrile group flanked by electron-donating methoxy and methyl substituents, enhancing its utility in constructing functionalized aromatic scaffolds. This bench-stable compound integrates readily into synthetic sequences requiring polar yet hydrophobic motifs.
4-Methoxy-2-methylbenzonitrile serves as a versatile building block in medicinal and process chemistry, enabling efficient access to substituted benzimidazoles and other heterocyclic scaffolds. Its ortho-methyl and para-methoxy substituents provide enhanced stability and favorable electronic modulation for electrophilic substitution and transition-metal-catalyzed coupling reactions. The nitrile group facilitates downstream transformations including hydrolysis to carboxylic acids or reductive amination, while the compound exhibits excellent bench stability and ease of purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: