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Structure of 21881-77-6
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m-Nifedipine features a meta-substituted pyridine core with a nitro group positioned ortho to the dihydropyridine ring, enhancing electron-withdrawing character. This configuration improves metabolic stability and facilitates selective calcium channel modulation in cardiovascular research applications.
m-Nifedipine serves as a well-established dihydropyridine scaffold for calcium channel modulator research, enabling direct evaluation of substitution effects on vascular smooth muscle activity. Its bench-stable crystalline form facilitates reproducible synthesis and purification, while the ortho-dialkylated pyridine core supports standard functional group interconversions and metal-catalyzed coupling reactions in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: