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CS-W001157 4
Total: USD 88.00

6-Methoxybenzo[d]thiazole-2(3H)-thione

  • CAS No. 2182-73-2

  • Cat. No. CS-0042733
  • Purity≥95%
  • MDL No.MFCD22003314

*For research and further manufacturing use only, not for direct human use.

6-Methoxybenzo[d]thiazole-2(3H)-thione|CS-0042733

Structure of 2182-73-2

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General Information

  • CAS No. 2182-73-2
  • Cat. No. CS-0042733
  • Purity ≥95%
  • MDL No. MFCD22003314
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇NOS₂
  • Molecular Weight 197.28
  • Synonym(s) 6-Methoxybenzothiazole-2-thiol
  • SMILES S=C1SC2=CC(OC)=CC=C2N1

Description

6-Methoxybenzo[d]thiazole-2(3H)-thione features a fused benzothiazole core with a methoxy group enhancing solubility and electronic modulation. This bench-stable heterocycle integrates readily into synthetic scaffolds for medicinal chemistry, offering a polarizable thione functionality ideal for metal coordination and bioactive compound development.

Application

6-Methoxybenzo[d]thiazole-2(3H)-thione serves as a versatile heterocyclic building block in medicinal chemistry and materials science. Its thione functionality enables reliable nucleophilic addition and metal-catalyzed coupling reactions, while the methoxy group enhances solubility and modulates electronic properties. The scaffold exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis of bioactive compounds and functionalized aromatic systems.

Synthesis

  • Route1
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      75-15-0
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      104-94-9
    • ~%
    • In-stock
      6-Methoxybenzo[d]thiazole-2(3H)-thione|CS-0042733
      2182-73-2

    References

    • Journal of the American Chemical Society, , vol. 45, p. 2395
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      140-89-6
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      2-Chloro-4-methoxyaniline|CS-W004703
      29242-84-0
    • ~%
    • In-stock
      6-Methoxybenzo[d]thiazole-2(3H)-thione|CS-0042733
      2182-73-2

    References

    • ACS Medicinal Chemistry Letters, , vol. 4, # 11 p. 1042 - 1047
  • Route3
    • null|null
      14372-55-5
    • ~%
    • In-stock
      6-Methoxybenzo[d]thiazole-2(3H)-thione|CS-0042733
      2182-73-2

    References

    • US1876929 , ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   25.02
  • LogP   2.96749
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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