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Structure of 21746-40-7
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N-(n-propyl)maleimide features a maleimide ring conjugated to a linear propyl chain, enabling efficient Michael addition with thiols under physiological conditions. This reactivity facilitates site-specific bioconjugation in protein labeling and antibody-drug conjugate synthesis. The n-propyl substituent enhances solubility and reduces aggregation compared to shorter alkyl analogs.
N-(n-propyl)maleimide serves as a versatile Michael acceptor and amine-reactive reagent, enabling site-specific conjugation in protein labeling and bioconjugation workflows. Its maleimide core facilitates rapid, selective addition across the double bond with thiols under physiological conditions, while the n-propyl substituent enhances solubility and metabolic stability compared to unsubstituted analogs. The compound exhibits excellent bench stability and ease of purification, making it well-suited for routine synthesis and derivatization in medicinal chemistry and probe development.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H302-H317
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P370+P378-P501
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Lot numbers can be found on the outside label of a product: