Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

N-(n-propyl)maleimide

  • CAS No. 21746-40-7

  • Cat. No. CS-0514978
  • Molecule weight139.15
  • Purity≥98%
  • MDL No.MFCD00014541

*For research and further manufacturing use only, not for direct human use.

N-(n-propyl)maleimide|CS-0514978

Structure of 21746-40-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 21746-40-7
  • Cat. No. CS-0514978
  • Purity ≥98%
  • MDL No. MFCD00014541
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉NO₂
  • Molecular Weight 139.15
  • Synonym(s) 1-Propyl-1H-pyrrole-2,5-dione
  • SMILES O=C(N1CCC)C=CC1=O

Description

N-(n-propyl)maleimide features a maleimide ring conjugated to a linear propyl chain, enabling efficient Michael addition with thiols under physiological conditions. This reactivity facilitates site-specific bioconjugation in protein labeling and antibody-drug conjugate synthesis. The n-propyl substituent enhances solubility and reduces aggregation compared to shorter alkyl analogs.

Application

N-(n-propyl)maleimide serves as a versatile Michael acceptor and amine-reactive reagent, enabling site-specific conjugation in protein labeling and bioconjugation workflows. Its maleimide core facilitates rapid, selective addition across the double bond with thiols under physiological conditions, while the n-propyl substituent enhances solubility and metabolic stability compared to unsubstituted analogs. The compound exhibits excellent bench stability and ease of purification, making it well-suited for routine synthesis and derivatization in medicinal chemistry and probe development.

Synthesis

  • Route1
    • null|null
      108-31-6
    • null|null
      107-10-8
    • ~20%
    • In-stock
      N-(n-propyl)maleimide|CS-0514978
      21746-40-7

    References

    • Katritzky, Alan R.; Fan, Wei-Qiang; Li, Qiao-Ling; Bayyuk, Shibli Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 885 - 892

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H302-H317
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P370+P378-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.38
  • LogP   0.3214
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • N-(n-propyl)maleimide sigmaN-(n-propyl)maleimide manufacturerN-(n-propyl)maleimide priceN-(n-propyl)maleimide structureN-(n-propyl)maleimide SDSbuy N-(n-propyl)maleimideN-(n-propyl)maleimide supplierN-(n-propyl)maleimide usesN-(n-propyl)maleimide molecular weightprice of N-(n-propyl)maleimideN-(n-propyl)maleimide chemical name formula of N-(n-propyl)maleimide
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label