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CS-W001157 4
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Fmoc-N-PEG24-acid

  • CAS No. 2170484-59-8

  • Cat. No. CS-0116429
  • Purity≥96%
  • MDL No.MFCD11041159

*For research and further manufacturing use only, not for direct human use.

Fmoc-N-PEG24-acid|CS-0116429

Structure of 2170484-59-8

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General Information

  • CAS No. 2170484-59-8
  • Cat. No. CS-0116429
  • Purity ≥96%
  • MDL No. MFCD11041159
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆₆H₁₁₃NO₂₈
  • Molecular Weight 1368.59
  • Synonym(s) None
  • SMILES O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)OCC1C(C=CC=C2)=C2C3=C1C=CC=C3

Description

Fmoc-N-PEG24-acid features a long, hydrophilic PEG24 chain anchored to an Fmoc-protected amine, enabling efficient solubility and reduced aggregation in peptide synthesis. This derivative facilitates site-specific conjugation and is compatible with standard coupling protocols under bench conditions.

Application

Fmoc-N-PEG24-acid serves as a versatile, high-molecular-weight linker for peptide and biomolecule conjugation. Its long PEG24 chain provides enhanced solubility and reduced aggregation in aqueous environments, while the Fmoc group enables efficient, orthogonal protection during solid-phase synthesis. The terminal carboxylic acid facilitates amide bond formation with primary amines, making it ideal for constructing multi-functionalized bioconjugates, PEGylated peptides, and macrocyclic scaffolds with improved pharmacokinetic profiles.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   297.15
  • LogP   3.3982
  • H_Acceptors   27
  • H_Donors   2
  • Rotatable_Bonds   77

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