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CS-W001157 4
Total: USD 88.00

3,7-Dibromo-10H-phenothiazine

  • CAS No. 21667-32-3

  • Cat. No. CS-0170220
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3,7-Dibromo-10H-phenothiazine|CS-0170220

Structure of 21667-32-3

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General Information

  • CAS No. 21667-32-3
  • Cat. No. CS-0170220
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₇Br₂NS
  • Molecular Weight 357.06
  • Synonym(s) 3,7-dibromo-phenothiazine
  • SMILES BrC1=CC(SC2=CC(Br)=CC=C2N3)=C3C=C1

Description

6-Chloropyridine-3-carboxylic acid (6-chloronicotinic acid/6-CNA) has been used to study its photolytic and photocatalytic degradation. The product has been used as a media component during the isolation of 6-CNA degrading bacterial strain from imidacloprid-exposed soil samples.

Application

3,7-Dibromo-10H-phenothiazine serves as a versatile brominated scaffold for late-stage functionalization in medicinal chemistry and materials science. The ortho-bromine substituents enable palladium-catalyzed cross-coupling reactions, facilitating the construction of biaryl architectures with high regiocontrol. Its inherent stability under standard reaction conditions and compatibility with diverse functional groups make it a practical building block for synthetic workflows requiring modular heterocyclic integration.

Synthesis

  • Route1

    References

    • Prosetta Antiviral, Inc. Patent: US2012/238543 A1, 2012 ; Location in patent: Page/Page column 12 ;
  • Route2

    References

    • Lin, Hsin-Hung; Su, Sheng-Yuan; Chang, Cheng-Chung Organic and Biomolecular Chemistry, 2009 , vol. 7, # 10 p. 2036 - 2039
  • Route3
    • null|null
      18621-99-3
    • ~%
    • In-stock
      3,7-Dibromo-10H-phenothiazine|CS-0170220
      21667-32-3

    References

    • Bodea,C.; Reileanu,M. J. Gen. Chem. USSR (Engl. Transl.), 1960 , vol. 30, # 4 p. 1131 - 1135,1148 - 1151

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   5.4198
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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