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CS-W001157 4
Total: USD 88.00

1,6-Dichlorohexane

  • CAS No. 2163-00-0

  • Cat. No. CS-W016259
  • Purity≥98%
  • MDL No.MFCD00001020

*For research and further manufacturing use only, not for direct human use.

1,6-Dichlorohexane|CS-W016259

Structure of 2163-00-0

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General Information

  • CAS No. 2163-00-0
  • Cat. No. CS-W016259
  • Purity ≥98%
  • MDL No. MFCD00001020
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂Cl₂
  • Molecular Weight 155.06
  • Synonym(s) None
  • SMILES ClCCCCCCCl

Description

1,6-Dichlorohexane serves as a linear, bifunctional halogenated alkyl linker for constructing molecular architectures. Featuring terminal chlorides on a six-carbon chain, it enables efficient coupling reactions in synthetic organic chemistry. This robust scaffold supports diverse transformations under standard conditions and offers predictable reactivity for polymer and small-molecule applications.

Application

1,6-Dichlorohexane serves as a versatile dihalogenated alkyl building block for the synthesis of polyether linkages and macrocyclic architectures. Its terminal chlorides enable efficient nucleophilic substitution reactions with amines, thiols, and alcohols under mild conditions, facilitating the construction of functionalized chains and heterocyclic frameworks. The molecule exhibits excellent bench stability and is compatible with common purification methods, making it a practical reagent for both academic and industrial synthetic workflows.

Synthesis

  • Route1

    References

    • BASF SE Patent: US2008/228016 A1, 2008 ; Location in patent: Page/Page column 5-6 ;
  • Route2
    • null|null
      2916-20-3
    • ~95%
    • In-stock
      1,6-Dichlorohexane|CS-W016259
      2163-00-0

    References

    • Violleau; Thiebaud; Borredon; Le Gars Synthetic Communications, 2001 , vol. 31, # 3 p. 367 - 373
  • Route3

    References

    • US2007/55084 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08,GHS09
Signal Word : Danger
UN#: 3082
Class : 9
Packing Group : Ⅲ
Hazard Statements : H304-H315-H411
Precautionary Statements : P210-P264-P273-P280-P302+P352-P331-P362+P364-P370+P378-P391-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.0244
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   5

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