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CS-W001157 4
Total: USD 88.00

(E)-3-(1H-Indol-6-yl)acrylic acid

  • CAS No. 215801-31-3

  • Cat. No. CS-0159322
  • Purity≥95%
  • MDL No.MFCD06205713

*For research and further manufacturing use only, not for direct human use.

(E)-3-(1H-Indol-6-yl)acrylic acid|CS-0159322

Structure of 215801-31-3

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General Information

  • CAS No. 215801-31-3
  • Cat. No. CS-0159322
  • Purity ≥95%
  • MDL No. MFCD06205713
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₉NO₂
  • Molecular Weight None
  • Synonym(s) (2E)-3-(1H-Indol-6-yl)acrylic acid
  • SMILES O=C(O)/C=C/C1=CC2=C(C=C1)C=CN2

Description

(E)-3-(1H-Indol-6-yl)acrylic acid features a conjugated enoic acid system linked to the indole scaffold, enabling direct integration into bioactive molecule synthesis. The planar (E)-configured double bond enhances electronic delocalization, while the carboxylic acid group facilitates derivatization. This compound serves as a key building block for indole-based pharmaceuticals and fluorescent probes.

Application

(E)-3-(1H-Indol-6-yl)acrylic acid serves as a versatile building block for synthesizing indole-based bioactive molecules, enabling efficient access to conjugated systems via [4+2] cycloadditions and Pd-catalyzed coupling reactions. Its well-defined (E)-configuration and bench-stable carboxylic acid functionality facilitate straightforward derivatization, purification, and integration into pharmaceutical scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   53.09
  • LogP   2.2657
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   2

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