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CS-W001157 4
Total: USD 88.00

1-Cyclopropylbutane-1,3-dione

  • CAS No. 21573-10-4

  • Cat. No. CS-W006361
  • Purity≥95%
  • MDL No.MFCD00511094

*For research and further manufacturing use only, not for direct human use.

1-Cyclopropylbutane-1,3-dione|CS-W006361

Structure of 21573-10-4

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General Information

  • CAS No. 21573-10-4
  • Cat. No. CS-W006361
  • Purity ≥95%
  • MDL No. MFCD00511094
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀O₂
  • Molecular Weight 126.15
  • Synonym(s) ACETOACETYL CYCLOPROPANE
  • SMILES CC(CC(C1CC1)=O)=O

Description

1-Cyclopropylbutane-1,3-dione features a cyclopropyl group flanking a 1,3-dione scaffold, delivering enhanced steric and electronic modulation. This configuration supports efficient enolization and facilitates use in asymmetric synthesis. The molecule exhibits robust stability under standard conditions while enabling selective C–C bond formation in complex molecular architectures.

Application

1-Cyclopropylbutane-1,3-dione serves as a versatile β-dicarbonyl building block in synthetic organic chemistry, enabling efficient construction of heterocyclic scaffolds and functionalized alkyl chains. Its cyclopropyl substitution enhances steric profile and electronic modulation, improving selectivity in enolate-based transformations. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for multi-step syntheses requiring controlled reactivity and functional group compatibility.

Synthesis

  • Route1
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      765-43-5
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      141-78-6
    • ~90%
    • In-stock
      1-Cyclopropylbutane-1,3-dione|CS-W006361
      21573-10-4

    References

    • Rozzey, Stuart J.; Fray, M. Jonathan Journal of Labelled Compounds and Radiopharmaceuticals, 2009 , vol. 52, # 10 p. 435 - 442
  • Route2

    References

    • US2003/100554 A1, ;
  • Route3
    • null|null
      765-43-5
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      108-24-7
    • ~%
    • In-stock
      1-Cyclopropylbutane-1,3-dione|CS-W006361
      21573-10-4

    References

    • Journal of Organic Chemistry, , vol. 17, p. 685,688

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   34.14
  • LogP   0.9446
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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