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CS-W001157 4
Total: USD 88.00

Dihydrogenistein

  • CAS No. 21554-71-2

  • Cat. No. CS-0030651
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Dihydrogenistein|CS-0030651

Structure of 21554-71-2

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General Information

  • CAS No. 21554-71-2
  • Cat. No. CS-0030651
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₂O₅
  • Molecular Weight 272.26
  • Synonym(s) None
  • SMILES O=C1C=2C(O)=CC(O)=CC2OCC1C3=CC=C(O)C=C3

Description

A potent, ATP-competitive, and specific inhibitor of casein kinase II (IC50 = 6 M). Reported to inhibit insulin-stimulated nuclear and cytosolic p70S6 kinase in CHO cells. Accentuates premature termination of transcription. Has been used to inhibit RNA polymerase II transcription which may be dependent on casein kinase II. Inhibits germinal vesicle breakdown in bovine oocytes. Induces G1/S cell cycle arrest.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P362+P364

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Computational Chemistry Data

  • TPSA   86.99
  • LogP   2.1623
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   1

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