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Structure of 21539-53-7
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3-(tert-Butylamino)propionitrile features a sterically hindered tertiary amine linked to a nitrile-bearing aliphatic chain, enabling stable incorporation into diverse synthetic scaffolds. This bench-stable building block facilitates efficient access to bioactive molecules through nucleophilic addition and coupling reactions under standard conditions.
3-(tert-Butylamino)propionitrile serves as a versatile building block for nitrile-containing scaffolds in medicinal chemistry and materials science. Its tert-butylamino group provides steric bulk and metabolic stability, while the terminal nitrile enables downstream transformations such as hydrolysis to carboxylic acids or reduction to primary amines. The molecule exhibits good bench stability, solubility in common organic solvents, and compatibility with standard functional group manipulations, facilitating efficient synthesis of complex intermediates and API precursors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: