Lot numbers can be found on the outside label of a product:
(4-Morpholinophenyl)methanamine
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CAS No. 214759-74-7
- Cat. No. CS-0035444
- Purity≥98%
- MDL No.None
*For research and further manufacturing use only, not for direct human use.
Structure of 214759-74-7
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General Information
- CAS No. 214759-74-7
- Cat. No. CS-0035444
- Purity ≥98%
- MDL No. None
- Storage -20°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₁H₁₆N₂O
- Molecular Weight 192.26
- Synonym(s) 4-Morpholinobenzylamine
- SMILES NCC1=CC=C(N2CCOCC2)C=C1
Description
(4-Morpholinophenyl)methanamine features a morpholine ring appended to a phenylmethanamine scaffold, delivering enhanced solubility and basicity. This electron-rich arylamine integrates readily into pharmaceutical intermediates and functional materials, offering robust performance under standard bench conditions.
Application
(4-Morpholinophenyl)methanamine serves as a versatile building block for constructing biologically relevant scaffolds, enabling efficient access to functionalized arylamines through standard coupling and derivatization protocols. Its morpholine moiety enhances solubility and provides a handle for further functionalization, while the primary amine facilitates conjugation reactions. Bench-stable and readily purified, it functions reliably in medicinal chemistry campaigns and heterocycle synthesis.
Synthesis
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Route1
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In-stock
10282-31-2 - ~22%
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In-stock
214759-74-7
References
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Abbott Laboratories Patent: US6933311 B2, 2005 ;
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Route2
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183557-77-9 - ~%
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In-stock
214759-74-7
References
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US2008/153843 A1, ; Page/Page column 47 ;
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Route3
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1001242-92-7
- ~%
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In-stock
214759-74-7
References
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Angewandte Chemie - International Edition, , vol. 46, # 43 p. 8266 - 8269
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3259
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 38.49
- LogP 0.9819
- H_Acceptors 3
- H_Donors 1
- Rotatable_Bonds 2
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Key Words
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