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CS-W001157 4
Total: USD 88.00

Vildagliptin impurity 24

  • CAS No. 214398-99-9

  • Cat. No. CS-0165388
  • Purity≥95%
  • MDL No.MFCD11845729

*For research and further manufacturing use only, not for direct human use.

Vildagliptin impurity 24|CS-0165388

Structure of 214398-99-9

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General Information

  • CAS No. 214398-99-9
  • Cat. No. CS-0165388
  • Purity ≥95%
  • MDL No. MFCD11845729
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁ClN₂O₂
  • Molecular Weight 190.63
  • Synonym(s) None
  • SMILES O=C([C@H]1N(C(CCl)=O)CCC1)N

Synthesis

  • Route1
    • (S)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid  Vildagliptin Impurity|CS-0165391
      23500-10-9
    • ~71%
    • Vildagliptin impurity 24|CS-0165388
      214398-99-9

    References

    • Xu, Xiaojian; Guo, Jianwei; Su, Qiang; Zhong, Xing Asian Journal of Chemistry, 2013 , vol. 25, # 13 p. 7557 - 7560
  • Route2

    References

    • Villhauer, Edwin B.; Brinkman, John A.; Naderi, Goli B.; Dunning, Beth E.; Mangold, Bonnie L.; Mone, Manisha D.; Russell, Mary E.; Weldon, Stephen C.; Hughes, Thomas E. Journal of Medicinal Chemistry, 2002 , vol. 45, # 12 p. 2362 - 2365
  • Route3
    • L-Proline Enalapril  Impurity|CS-0229432
      147-85-3
    • ~%
    • Vildagliptin impurity 24|CS-0165388
      214398-99-9

    References

    • Xu, Xiaojian; Guo, Jianwei; Su, Qiang; Zhong, Xing Asian Journal of Chemistry, 2013 , vol. 25, # 13 p. 7557 - 7560

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.4
  • LogP   -0.2985
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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