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CS-W001157 4
Total: USD 88.00

1-(4-Fluorophenyl)cyclopentane-1-carboxylic acid

  • CAS No. 214262-99-4

  • Cat. No. CS-0132694
  • Purity≥96%
  • MDL No.MFCD00800626

*For research and further manufacturing use only, not for direct human use.

1-(4-Fluorophenyl)cyclopentane-1-carboxylic acid|CS-0132694

Structure of 214262-99-4

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General Information

  • CAS No. 214262-99-4
  • Cat. No. CS-0132694
  • Purity ≥96%
  • MDL No. MFCD00800626
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₃FO₂
  • Molecular Weight 208.23
  • Synonym(s) 1-(4-Fluorophenyl)Cyclopentanecarboxylic Acid,
  • SMILES O=C(C1(C2=CC=C(F)C=C2)CCCC1)O

Description

This cyclopentane carboxylic acid derivative features a para-fluorophenyl group that enhances lipophilicity and metabolic stability. The rigid cyclopentane scaffold provides conformational control, while the carboxylic acid moiety enables direct conjugation or salt formation. Ideal for medicinal chemistry applications requiring balanced solubility and membrane permeability.

Application

1-(4-Fluorophenyl)cyclopentane-1-carboxylic acid serves as a valuable building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard functional group manipulations. Its cyclopentane core provides conformational rigidity, while the 4-fluorophenyl and carboxylic acid groups offer orthogonal reactivity for derivatization via amide coupling, esterification, or metal-catalyzed cross-coupling. Bench-stable and readily purified by recrystallization, it functions effectively in peptide-like and heterocyclic synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.7221
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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