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CS-W001157 4
Total: USD 88.00

1-(2,6-Dimethylphenyl)ethan-1-one

  • CAS No. 2142-76-9

  • Cat. No. CS-W005839
  • Purity≥97%
  • MDL No.MFCD01861394

*For research and further manufacturing use only, not for direct human use.

1-(2,6-Dimethylphenyl)ethan-1-one|CS-W005839

Structure of 2142-76-9

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General Information

  • CAS No. 2142-76-9
  • Cat. No. CS-W005839
  • Purity ≥97%
  • MDL No. MFCD01861394
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂O
  • Molecular Weight 148.20
  • Synonym(s) 1-(2,6-Dimethylphenyl)ethanone
  • SMILES CC(=O)C1=C(C)C=CC=C1C

Description

1-(2,6-Dimethylphenyl)ethan-1-one features a sterically hindered aromatic ring flanked by two methyl groups, enhancing its stability and solubility in organic media. This ketone integrates readily into synthetic sequences requiring electron-rich aryl moieties, offering predictable reactivity under standard conditions.

Application

1-(2,6-Dimethylphenyl)ethan-1-one serves as a versatile aryl ketone building block in synthetic organic chemistry, enabling efficient construction of biaryl and heterocyclic scaffolds. Its stability under standard reaction conditions, combined with predictable electrophilic reactivity at the carbonyl center, facilitates direct functionalization and coupling transformations. The ortho-methyl groups provide steric shielding and enhance bench stability, simplifying purification and handling in multi-step syntheses.

Synthesis

  • Route1
    • null|null
      75-36-5
    • null|null
      108-38-3
    • ~92%
    • In-stock
      1-(2,6-Dimethylphenyl)ethan-1-one|CS-W005839
      2142-76-9

    References

    • Karthik; Kulangiappar; Marken, Frank; Kulandainathan, M. Anbu Tetrahedron Letters, 2008 , vol. 49, # 16 p. 2625 - 2627
  • Route2
    • In-stock
      2,6-Dimethylstyrene|CS-0158030
      2039-90-9
    • ~%
    • In-stock
      1-(2,6-Dimethylphenyl)ethan-1-one|CS-W005839
      2142-76-9
    • null|null
      27843-11-4

    References

    • Chemistry - A European Journal, , vol. 12, # 3 p. 949 - 955
  • Route3
    • null|null
      87-62-7
    • ~%
    • In-stock
      1-(2,6-Dimethylphenyl)ethan-1-one|CS-W005839
      2142-76-9

    References

    • Organic Mass Spectrometry, , vol. 28, # 10 p. 1107 - 1110

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.50604
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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