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CS-W001157 4
Total: USD 88.00

Thalidomide-NH-PEG3-propionic acid

  • CAS No. 2138440-82-9

  • Cat. No. CS-0120147
  • Purity≥97%
  • MDL No.MFCD32173779

*For research and further manufacturing use only, not for direct human use.

Thalidomide-NH-PEG3-propionic acid|CS-0120147

Structure of 2138440-82-9

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General Information

  • CAS No. 2138440-82-9
  • Cat. No. CS-0120147
  • Purity ≥97%
  • MDL No. MFCD32173779
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₂₇N₃O₉
  • Molecular Weight 477.46
  • Synonym(s) None
  • SMILES O=C(O)CCOCCOCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O

Description

Yttrium(III) 2-ethylhexanoate has been used for research in nanotechnology based applications.

Application

Thalidomide-NH-PEG3-propionic acid serves as a bifunctional linker for targeted conjugation, combining the pharmacophoric thalidomide moiety with a PEG3 spacer and carboxylic acid handle. The propionic acid group enables facile amide coupling, while the PEG3 segment enhances solubility and reduces aggregation. This reagent facilitates site-specific bioconjugation in antibody-drug conjugates and PROTACs, offering improved stability and predictable conjugation efficiency in aqueous media.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H361
Precautionary Statements : P280-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   160.57
  • LogP   0.0242
  • H_Acceptors   9
  • H_Donors   3
  • Rotatable_Bonds   14

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